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What's Next on the Big C?

(Hope­fully a second opinion)

When I last wrote on The Big C, a Showtime series in which the actress Laura Linney por­trays a woman in her forties with advanced melanoma, I con­sidered some of the options she might choose when the series resumes next Monday night.

Laura Linney, in Showtime’s ‘Big C’

At the end of Season 1, she elected to try a course of IL-​​2 as was rec­om­mended by her young oncol­ogist. Mean­while, the FDA has approved Ipil­i­mumab (Yervoy), an antibody treatment that revs up the immune system. And she’s in line, according to the script, for pos­sible entry into a clinical trial that likely involves a tar­geted therapy, like vemu­rafenib for patients whose malignant cells have a genetic mutation in B-​​RAF.

What I expect Cathy will do, before any­thing else happens and she receives any addi­tional non-​​urgent treatment for her advanced melanoma, is get a second opinion. She’s a smart, sen­sible sort; in ret­ro­spect it’s hard to believe she didn’t do this earlier on and before starting the IL-​​2 therapy.

I wonder, also, if one of her family members or friends will do some research about melanoma on the Internet. That would help her find a doctor with appro­priate expertise, and better know what ques­tions she should ask of the oncol­ogist during the consultation.

That’s all on Cathy’s decision, until next week.

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1 comment to What’s Next on the Big C? (Hopefully a Second Opinion)

  • Thanks for the heads-​​up Elaine. Let’s hope that either Cathy or her family fol­lowed the ASCO proceedings.…or the ACOR list …can’t imagine having cancer NOW, without the internet.

    Jody

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