The harsh reality is that people who have had cancer treatment are sometimes perceived as a burden on a working group
As for 10 months of PFS, that’s valuable. Imagine that you’re 55 years old and living with metastatic breast cancer. A drug that is likely to delay, by most of 2 years, your tumor’s expansion into the lungs …A concern I have is that this study wasn’t blinded,
The problem with Tamoxifen is that it has anti-estrogen effects that many young (and older) women consider undesirable. Already our breasts have been cut. Feeling “feminine” is not trivial.
This kind of paternalism, when a doctor assesses the risks and benefits, and spares the patient’s “knowing” seems anachronistic. But it may, still, be what many people are looking for when and if they get a serious illness. Not everyone wants a “tell me everything” kind of physician.
This news reminds us an aspect of cancer treatment some of us would rather put out of our heads….all cancer patients should take careful notes on their planned treatments and ask their doctors about the long-term consequences of therapy.
The new agent is a hybrid of an old monoclonal antibody, Herceptin, that’s chemically attached to DM1, a traditional kind of chemotherapy. The preliminary results of this randomized trial are encouraging. …It’s hard to know how this promising, likely expensive, intravenous drug will fit in with others for patients with Her2+ breast cancer.
The 10 molecular BC categories bear prognostic (survival) information and, based on their distinct mutations and gene expression patterns, potential targets for novel drugs….I wonder if, in a few years, some breast cancers might be treated without surgery.