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Communication | Diagnosis | Health IT | Medical News | Psychiatry | Tuesday Term

Cyberchondria Rising - What is the Term's Meaning and History?

Yes­terday the AMA news informed me that cyber­chondria is on the rise. So it’s a good moment to con­sider the term’s meaning and history.

Cyber­chondria is an unfounded health concern that develops upon searching the Internet for infor­mation about symptoms or a disease. A cyber­chon­driac is someone who surfs the Web about a medical problem and worries about it unduly.

Through Wikipedia, I located what might be the first ref­erence to cyber­chondria in a medical journal: a 2003 article in the Journal of Neu­rology, Neu­ro­surgery, and Psy­chiatry. A section on the new diag­nosis starts like this: “Although not yet in the Oxford English Dic­tionary, the word ‘cyber­chondria’ has been coined to describe the excessive use of internet health sites to fuel health anxiety.” That aca­demic report links back to a 2001 story in the Inde­pendent, “Are you a Cyberchondriac?”

Two Microsoft researchers, Ryen White and Eric Horvitz, authored a “classic” paper: Cyber­chondria: Studies of the Esca­lation of Medical Concerns

See more Cyber­chondria Rising — What is the Term’s Meaning and History?

Aging | Movies | Women's Health

The Iron Lady, a Film About an Aging Woman

Iron Lady Meryl Streep

image, “the Iron Lady”

Over the weekend I saw the Iron Lady, a movie about Mar­garet Thatcher, the former Prime Min­ister of England.  I expected a top-​​​​notch, accented and nuanced per­for­mance by Meryl Streep, and got that.

The film sur­prised me in several respects. It’s really about aging, and how a fiercely inde­pendent woman withers. The camera takes you within her elderly, blurry, husband-​​​​conjuring mind. She’s for­getful and ram­bling, but main­tains an interest in current events, and ideas. She looks back on events in her life with pride and, seem­ingly, some regrets.

Well done, worth seeing!

— Adver­tise­ments:

Related Posts:Another Take On An Ordinary DayThe “Sur­vivor” Term After Breast Cancer: Is There a Better Expression?Harsh Words, and Women’s Health at Risk50–50, A Serious Film About a Young Man With a Rare Can­cerKomen Update –

See more The Iron Lady, a Film About an Aging Woman

health care costs | Policy | Public Health

Notes on Wendell Potter, and Why Companies Support the Individual Mandate

amazon Deadly Spin

The current debate about the indi­vidual mandate reminded me to post this -

About a year ago, I had the oppor­tunity to hear Wendell Potter, author of Deadly Spin - an insider’s sharp cri­tique of the insurance industry, speak at a meeting of the New York Met­ro­politan Chapter of Physi­cians for a National Health Program. Despite the cold, dark winter night and midtown drea­riness of the meeting location, the large lecture room was packed. I arrived well before Potter’s pre­sen­tation but couldn’t get a copy of his book; they’d sold out.

The meeting was instructive: I got a sense of Potter’s per­sonal story (he’s from Ten­nessee, and lived for a while in Appalachia), his pre­vious career (he worked as a jour­nalist, turned to mar­keting, even­tually led PR for Cigna) and his per­spective on how people in the health care industry use lan­guage to frame the debate on health care reform. Since 2009, when he left his position at Cigna, he writes and

See more Notes on Wendell Potter, and Why Com­panies Support the Indi­vidual Mandate

Academic Medicine | clinical trials | Infectious Disease

NEJM Reports on 2 New Drugs for Hepatitis C

Last week’s NEJM delivered an intriguing, imperfect article on a new approach to treating hepatitis C (HCV). The paper’s careful title, Pre­lim­inary Study of Two Antiviral Agents for Hepatitis C Genotype 1, seems right. The analysis, with 17 authors listed, traces the response of 21 people with hepatitis C (HCV) who got two new anti-​​​​viral agents, with or without older drugs, in a clinical trial spon­sored by Bristol-​​​​Meyers Squibb.

The 21 study par­tic­i­pants all had chronic infection by HCV genotype 1, a strain that’s common in North America and rel­a­tively resistant to standard treatment. All sub­jects were between 18 and 70 years old, with a mea­surable level of HCV RNA in the blood, no evi­dence of cir­rhosis, and no response to prior HCV treatment (according to cri­teria detailed in the paper). In the trial, 11 patients received a com­bi­nation regimen of daclatasvir (60 mg once daily, by mouth) and asunaprevir (600 mg, twice daily by mouth) alone; the other 10 patients took the exper­i­mental drugs

See more NEJM Reports on 2 New Drugs for Hepatitis C

Blogs | Communication | Social Media | Wednesday Web Sighting

Dr. Val Jones Hosts Grand Rounds at USA Today

Yes­terday Dr. Val Jones, @DrVal, took med-​​​​blog Grand Rounds to a new level. She poured through over 100 entries, and pub­lished 55 syn­opses at USA Today’s Healthy Per­spective column.

There are 4 parts:

Health Tips

True Stories

Myth-​​​​busters and Controversies

Health Care Costs

Con­grat­u­la­tions, and thanks, to Val for pulling together so much thoughtful work!

Related Posts:Med-​​Blog Grand Rounds Takes a Virtual TourAn­nouncement for Next Week’s Med-​​​​Blog Grand RoundsHot Topics: This Week’s Med-​​​​Blog Rounds at Bedside Man­nerWhy Should Physi­cians Blog or Use Twitter?Shoutout to Shrink Rap

cancer treatment | Oncology (cancer) | Statistics | Tuesday Term

What is the Disease Control Rate in Oncology?

Last week I came upon a new term in the cancer lit­er­ature: the Disease Control Rate. The DCR refers to the total pro­portion of patients who demon­strate a response to treatment.

In oncology terms: The DCR is the sum of com­plete responses (CR) + partial responses (PR) + stable disease (SD).

Another way of explaining it: Some people with cancer have mea­surable, growing tumors. For example, a man might have a sarcoma with mul­tiple metas­tases in the lung that are evi­dently pro­gressing. If the patient starts a new treatment and the lung mets don’t shrink but stop getting bigger, that might be con­sidered a sta­bi­lizing effect from the therapy, and his response would be included in the DCR. —

Related Posts:Low­ering Cancer Care Costs by Reducing Tests After Treat­ment­Defining a Cluster of Dif­fer­en­ti­ation, or CDReview: Dr. Eric Topol’s Cre­ative Destruction of Med­i­cineNew Studies on Colon Cancer Screening by Colonoscopy and Fecal Blood Testing50–50, A Serious Film About a Young Man With a Rare Cancer

from the author | Future of Medicine | Health IT | Policy | Privacy

The 'Journal' Asks, Should Patients Have Identification Numbers?

Today’s Wall Street Journal includes a special Big Issues health care section. A post on their blog caught my attention: Should Patient Have Elec­tronic Iden­ti­fi­cation Numbers?

The idea is that people who use health care would each be assigned a uni­versal patient iden­tifier, or UPI. This unique number would link to a person’s health records. In prin­ciple it would facil­itate transfer of a patient’s medical history between doctors, hos­pitals and, likely, insurance com­panies. There are argu­ments pro – mainly having to do with effi­ciency and patient safety; and against – mainly having to do with privacy.

My issue is that it reminds me of Auschwitz. But apart from that par­ticular asso­ci­ation, labeling people with numbers seems dehu­man­izing — what’s already a big neg­ative in modern health care. I/​​we need to realize that already we have numbers. Most people have social security numbers. I have several hos­pital ID numbers and insurance company numbers.

As for privacy, that’s

See more The ‘Journal’ Asks, Should Patients Have Iden­ti­fi­cation Numbers?

Homemaking | Medical News | Nutrition | Public Illness | Women's Health

A Good Outcome from Celebrity Chef Paula Deen’s Message about Diabetes?

Paula Deen's new message

Paula Deen’s new message

I never heard of Paula Deen until this week, when the plump Food Channel celebrity and cookbook author announced she has Type 2 dia­betes. The Georgia-​​​​born, sweet tea-​​​​loving cook has teamed up with Novo Nordisc to spread the word about dietary mod­i­fi­cation and life with dia­betes. Her new platform, Dia­betes in a New Light, high­lights a drug she’s taking called Victoza.

Type 2 dia­betes tends to develop in over­weight people who become resistant to insulin. Thi disease is epi­demic in North America; it affects over 8 percent of the pop­u­lation. Almost 95 percent of adult-​​​​onset dia­betes cases are Type 2; many could be avoided by diet and lifestyle mod­i­fi­cation. Dia­betes causes blood vessel abnor­mal­ities throughout the body; it leads to sec­ondary ill­nesses like heart disease, stroke, poor vision and blindness, kidney problems, neu­ropathy and other serious health problems. It’s a costly disease, apart from the medical effects; The NIH estimates

See more A Good Outcome from Celebrity Chef Paula Deen’s Message about Diabetes?

cancer treatment | clinical trials | Medical News | Oncology (cancer)

Regorafenib, an Experimental Pill Tested in Colon and Rectal Cancer Patients, on Conference Agenda

Tomorrow the American Society of Clinical Oncology* will host its 9th annual GI Cancers Sym­posium. Bloomberg and the LA Times have already reported findings of a paper, still in abstract form, to be pre­sented on Saturday.

The drug of interest is rego­rafenib, a pill that loosely inhibits quite a few kinases – enzymes critical in cell signals that control growth of normal cells, tumors and blood vessels. The exper­i­mental med, man­u­fac­tured by Bayer, is also known as BAY 73–4506. The new data emerge from an inter­na­tional, ran­domized Phase III trial that goes by a loaded acronym: CORRECT.

The study included 760 patients with advanced colon or rectal cancer whose tumor pro­gressed after receiving standard treat­ments. Par­tic­i­pants received either the study drug or BSC (best sup­portive care) and a placebo. According to the paper, BSC includes antibi­otics, pain meds, radi­ation for bone mets, steroids and some other treatments. The median sur­vival in patients who received the

See more Rego­rafenib, an Exper­i­mental Pill Tested in Colon and Rectal Cancer Patients, on Con­ference Agenda

Books | history | Oncology (cancer) | Science

The Emperor of All Maladies: A Detailed Narrative of Cancer History and Ideas

This week I fin­ished reading the Emperor of All Mal­adies, the 2010 “biog­raphy” of cancer by Dr. Sid­dhartha Mukherjee. The author, a medical oncol­ogist and researcher now at Columbia Uni­versity, pro­vides a detailed account of malig­nancies – and how physi­cians and sci­en­tists have under­stood and approached a myriad of tumors – through history.

The ency­clo­pedic, Pulitzer Prize-​​​​winning book is rich with details. In the first half, Mukherjee focuses on clinical aspects of malig­nancy. He works both ancient and modern stories into the nar­rative; the reader learns of Atossa, the Persian queen of the 6th Century BCE who covered her breast disease, and Thomas Hodgkin, who in the 19th Century dis­sected cadavers and noted a “peculiar” pattern of glan­dular swelling in some young men, and Einar Gustafson, aka Jimmy, who was among the first children cured of leukemia in the 1950s.

The second half is a tour-​​​​de force on cancer biology; the author winds dis­tinct threads

See more The Emperor of All Mal­adies: A Detailed Nar­rative of Cancer History and Ideas

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