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cancer treatment | clinical trials | Communication | Medical News | Oncology (cancer) | Science

Today's Press on Targeted Therapy for Cancer

Today the NY Times printed the third part of Amy Harmon’s excellent feature on the ups and downs and promise of some clinical trials for cancer. The focus is on a new drug, PLX4032, some people with melanoma who chose to try this exper­i­mental agent, and the oncol­o­gists who pre­scribed it to them. What I like about this story is that, besides offering some insight on the drug itself, it bal­ances the patients’ and doctors’ per­spec­tives; it explains why some people might elect to take a new med­ication in an early-​​stage clinical trial and why some physi­cians push for these pro­tocols because they think it’s best for their patients. And it pro­vides a window into the world of aca­demic med­icine, where doctors’ col­lab­orate among them­selves and some­times with cor­po­ra­tions. Here’s some of what I learned:

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Breast Cancer | cancer survival | Reviews | TV

The New Boss on The Office is a Breast Cancer Survivor

Jo Bennett, Sabre CEO and BC Survivor

There’s a new sur­vivor on TV and she means business. In the latest episode of The Office, Kathy Bates walked into the Scranton branch of Dundler Mifflen and onto my living room TV screen as Jo Bennett, CEO of Sabre, a fic­ti­tious Tallahassee-​​based company. An assistant and two large canines accompany her as she meets the crew. She’s firm, graying and very much-​​in-​​charge. When the camera gets her alone, in focus, here’s what she has to say: “I’m Jolene Bennett, Jo for short. “I’m a breast cancer sur­vivor, close per­sonal friends with Nancy Pelosi, and Truman Capote and I slept with three of the same guys. When I was a little girl I was ter­rified to fly, and now I have my own pilot’s license. “I am CEO of Sabre Inter­na­tional and I sell the best damn printers and all-​​in-​​one machines Korea can make. “Pleased to meet ya.

See more New Boss on The Office is a Breast Cancer Survivor

Breast Cancer | cancer survival | cancer treatment | Medical News | Oncology (cancer) | Women's Health

News on Aspirin after Breast Cancer

Aspirin Use, Relative Risk for Death from Breast Cancer

There’s promising news on the breast cancer front. A study pub­lished on-​​line this week in The Journal of Clinical Oncology (JCO) sug­gests that regular, low-​​dose aspirin use reduces the risk of recur­rence and death from breast cancer among women who’ve had stage I, II or III (non-​​metastatic) disease. This is a phe­nomenal report in three respects: 1. The dra­matic results: among women who’ve had breast cancer, regular aspirin use was asso­ciated with a reduced risk of recur­rence and of death from cancer by more than half; 2. The rel­e­vance; these findings might affect mil­lions of women living after breast cancer, today; 3. The cost: aspirin is widely available without patent restriction. Aspirin costs around $5 for 100 tablets, several months’ supply.

See more News on Aspirin After Breast Cancer

health care costs | Ideas | Medical Ethics | Policy | Public Health | Radio

You're Sick and I'm Not, Too Bad

“The insurance market as it works today basi­cally slices and dices the pop­u­lation. It says, well you people with medical con­di­tions, over here, and you people without them, over here… — Jonathan Cohn, Editor of The New Republic, speaking on The Brian Lehrer Show, Feb­ruary 16, 2010* —– There’s a popular, partly true, some­times useful and very dan­gerous notion that we can control our health. Maybe even fend off cancer. I like the idea that we can make smart choices, eat sen­sible amounts of whole foods…

See more You’re Sick and I’m Not, Too Bad (on Empathy)

cancer treatment | Communication | Empowered Patient | health care costs | Informed Consent | Medical Ethics | Patient Autonomy

Health Care Costs, Communication and Informed Choices

For those of you who’ve been asleep for the past year: the health care costs conundrum remains unsolved. Our annual medical bills run in the neigh­borhood of $2.4 trillion and that number’s heading up. Reform, even in its watered-​​down, red­dened form, has stalled. Despite so much unending review of medical expenses – attributed var­i­ously to an unfit, aging pop­u­lation, expensive new cancer drugs, inno­v­ative pro­ce­dures, insurance com­panies and big Pharma — there’s been sur­pris­ingly little con­sid­er­ation for patients’ pref­er­ences. What’s missing is a solid dis­cussion of the type and extent of treat­ments people would want if they were suf­fi­ciently informed of their medical options and cir­cum­stances. Maybe, if doctors would ask their adult patients how much care they really want, the price of health care would go down. That’s because many patients would choose less, at least in the way of tech­nology, than their doctors pre­scribe. And more care. What I’m talking about is the opposite of rationing. It’s about choosing.

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Communication | Life | Life as a Patient | Life in NYC | Medical Education | Medical Ethics | Movies | Patient Autonomy | Reviews | Women's Health

On Precious

Poster for Precious, the film based on the novel "Push," by Sapphire

This is my first film review, if it is that. I was tempted to write about Ethan Hawke, hema­tol­ogist among vam­pires in Day­breakers, but gore’s not my favorite genre. A main­stream choice would have been Har­rison Ford solving the enzyme defi­ciency of Pompe disease in Extra­or­dinary Mea­sures, but I didn’t get sucked in. I chose Pre­cious, instead. This luminous movie relates to the practice of med­icine everyday, big-​​time.

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Books | Communication | Ideas | Informed Consent | Life as a Patient | Medical Education | Medical Ethics | Oncology (cancer) | Patient Autonomy | Patient-Doctor Relationship | Privacy | Reviews | Science | Women's Health

Henrietta's Cells Speak

“One of the ways that I gained the trust of the family is that I gave them infor­mation.” (R. Skloot, a jour­nalist, speaking about her inter­ac­tions with Hen­rietta Lacks’ family, Columbia Uni­versity, 2/​2/​10)

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Communication | Empowered Patient | Health IT | Life as a Doctor | Patient-Doctor Relationship | Public Health | Social Media

Are Doctors Necessary?

Ten years ago, my col­leagues and I squirmed in our swivel chairs when a few tech-​​savvy patients filed in bearing reams of articles they’d dis­covered, down­loaded and printed for our perusal. Some of us accepted these infor­ma­tional “gifts” warily, half-​​curious about what was out there and half-​​loathing the prospect of more reading. Quite a few com­plained about the changing infor­ma­tional dynamic between patients and their physi­cians, threatened by a per­ceived and perhaps real loss of control. How a decade can make a dif­ference. In 2008 over 140 million Americans…

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from the author | Social Media

Feb 1, 2010

Well, the blog’s in some sort of tran­si­tional state between web hosts. (No one taught me about FTPs in med school, and blogs didn’t exist then. The “web” didn’t either, in fact.) It seems we need wait until tomorrow which, it happens, is Groundhog’s Day. It should be sunny, right? –ES

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