A Film and Story-Telling Festival Focuses on Disability
The program featured a dizzying spectrum of disability perspectives and concerns on film. It also included talks, photographs, parties and story-telling in presented by “The Moth.”
10 Newly-Defined Molecular Types of Breast Cancer in Nature, and a Dream
The 10 molecular BC categories bear prognostic (survival) information and, based on their distinct mutations and gene expression patterns, potential targets for novel drugs….I wonder if, in a few years, some breast cancers might be treated without surgery.
Blood and Hip Surgery: New Study Supports Fewer Transfusions
Under the radar, over the holiday week, the NEJM published a report on transfusion requirements in older adults who surgical hip repair. The main finding is that most patients, including the elderly and those at risk for cardiac complications of the procedure, don’t benefit from getting so many red blood cell transfusions as is commonly […]
New Music from an Orchestra of Radioactive Isotopes
For the weekend – A tweet led me to a fantastically inventive kind of music. The Radioactive Orchestra comprises 3175 radioisotopes. From the website: “Melodies are created by simulating what happens in the atomic nucleus when it decays from its excited nuclear state…Every isotope has a unique set of possible excited states and decay patterns…” The project, […]
Cervical Cancer Screening Update: on Pap Smears, Liquid-based Cytology and HPV
The latest issue of the Annals of Internal Medicine contains 2 noteworthy papers on cervical cancer screening. The first, a systematic review of studies commissioned by the USPSTF, looked at 3 methods for evaluating abnormalities in women over 30 years: 1. Conventional cytology (as in a Pap smear; the cervix is scraped and cells splayed […]
New Study, Presented at a Meeting of Breast Surgeons, Supports that Mammograms Save Lives of Women in Their 40s
The American Society of Breast Surgeons held its 2011 annual meeting in D.C. from April 27 – May 1. Among the papers presented was Abstract #1754: “Mammography in 40 Year Old Women: The Potential Impact of the U.S. Preventative Services Task Force (USPSTF) Mammography Guidelines.” You can find the press release, followed by the abstract, […]
When Less Chemo is Just As Good, In Treatment for Acute Myeloid Leukemia (AML)
Today’s issue of the New England Journal of Medicine includes an article with the bland title Cytarabine Dose for Acute Myeloid Leukemia. AML is an often-curable form of leukemia characterized by rapidly-growing myeloid white blood cells. Cytarabine – what we’d call “Ara-C” on rounds – has been a mainstay of AML treatment for decades. The […]
Radiologists’ Experience Matters in Mammography Outcomes
There’s a new study out on mammography with important implications for breast cancer screening. The main result is that when radiologists review more mammograms per year, the rate of false positives declines. The stated purpose of the research,* published in the journal Radiology, was to see how radiologists’ interpretive volume – essentially the number of […]
More News On Lymph Nodes and Breast Cancer Surgery
Last week the New England Journal of Medicine (NEJM) printed a major research article on lymph node dissection in breast cancer surgery. When I first saw the Times’ recent headline, I thought it would cover this paper: Effect of Occult Metastases on Survival in Node-Negative Breast Cancer.*
It turns out there were separate articles on axillary node dissection after sentinel node biopsy in breast cancer – one in JAMA and one in the NEJM – published a week apart. For some reason, the NEJM paper got little attention…
Cautious Optimism for a New Melanoma Treatment
This morning’s news feed delivered some seemingly excellent news for some people with melanoma. At least until now, this form of skin cancer has been considered incurable when metastatic. In the last year, we heard details about the ups and downs of ongoing clinical trials of new drugs to treat the disease. The Times reports […]