Science Takes a Double Hit in the Press, Maybe

In his latest New Yorker piece The Truth Wears Off, Jonah Lehrer directs our attention to the lack of reproducibility of results in scientific research. The problem is pervasive, he says: …now all sorts of well-established, multiply confirmed finding have started to look increasingly uncertain. It’s as if our facts were losing their truth: claims […]

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Twitter, The Notificator, and Old Social Media News

A series of clicks this morning brought me to an interesting web finding in a Wiki-like Dead Media Archive that links to NYU’s Steinhart School of Media, Culture, and Communication. And there rests the Notificator, said (by me) to be Twitter’s great-great-great grandfather, with details: On September 9, 1932, the London Times printed an article […]

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Considering Evidence for a New Drug for Immune Thrombocytopenia Purpura

I’ve been wondering, lately, why so many of the medical blogs cover the same topics, like last week’s lung cancer detection trial, which are often the exact same studies as are reported by conventional news outlets. I’ve been trying, here, to sometimes consider new published articles that seem important to me but, for whatever reasons, don’t get so much attention.

Here’s one:

Yesterday’s NEJM includes an article Romiplostim or Standard of Care in Patients with Immune Thrombocytopenia.* It’s about a drug, manufactured and sold by Amgen as NPlate, that received FDA approval for treatment of chronic immune thrombocytopenia purpura (ITP) in August, 2008. Some consider ITP a rare disease, and

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A Play About the Life and Work of Dr. Rosalind Franklin

Franklin’s story starts like this: She was born in 1920 to a Jewish family in London. She excelled in math and science. She studied physical chemistry at Cambridge, where she received her undergraduate degree in 1941. After performing research in photochemistry in the following year on scholarship, she joined the British Coal Utilisation Research Association (BCURA) and carried out basic investigations on the micro-structure of coal and carbon compounds, and so earned a Ph.D. from Cambridge University. She was a polyglot, and next found herself in Paris at the Laboratoire Central des Services Chimique de l’Etat, where she picked up some fine skills in x-ray crystallography.

You get the picture: she was smart, well-educated and totally immersed in physical chemistry before, during and after WWII. Single-minded and focused, you might say –

Posted in Essential Lessons, Medical History, Occupational health, Reviews, Science, Theater, Women's HealthTagged , , , , , , , , , 1 Comment on A Play About the Life and Work of Dr. Rosalind Franklin

No Quick Fix

“If it’s chafed, put some lotion on it.”

– some practical advice, offered by the character portraying Andrew Jackson, speaking toward the audience in the last scene of Bloody Bloody Andrew Jackson, a play written and directed by Alex Timbers

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Stem Cells, Breast Reconstruction and a Magazine Cover

The cover of the November print edition of Wired features large, unnatural-appearing cleavage. Inside and toward the back of the issue, a curious article ties together stem cells and the future of breast reconstruction. It got my attention. The detailed and admittedly interesting piece, by Sharon Begley, describes what’s science or science fiction: first humans, […]

Posted in Breast Cancer, cancer treatment, Future of Medicine, Magazine, Plastic and Reconstructive Surgery, ScienceTagged , , , , , , 1 Comment on Stem Cells, Breast Reconstruction and a Magazine Cover

Word of the Week: floccinaucinihilipilificationism

ML learned a new word upon reading the newspaper: floccinaucinihilipilificationism. According to the New York Times now, Moynihan prided himself on coining the 32-letter mouthful, by which he meant “the futility of making estimates on the accuracy of public data.”

She’s not exactly sure how the term, said to be the longest non-technical word in the English language, might be used in medical communication, but it seems that it might be relevant to estimating health care costs, and – possibly by extrapolation – to understanding the hidden ambiguousness of inferences drawn from vast amounts of seemingly hard data.

Posted in Communication, language, StatisticsTagged , , , , , 1 Comment on Word of the Week: floccinaucinihilipilificationism

A Lead Poisoning Outbreak in Nigeria, Plumbism and Anemia

Over 400 Nigerian children have died from lead poisoning this year…lead poisoning is sometimes called plumbism, stemming from plumbum, the Latin term for lead (Pb, atomic number 82), a metal used by plumber. A rarer term is Saturnism, based on the metal’s association with that planet and ancient Roman god.

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What’s Missing in the Recent Mammography Value Study

I’d say the oppo­site is true: It’s pre­cisely because there are effec­tive treat­ments for early-stage dis­ease that it’s worth find­ing breast can­cer early. Oth­er­wise, what would be the point?

Metasta­tic breast can­cer is quite costly to treat and, even with some avail­able tar­geted ther­a­pies, remains

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Perspective on Screening for Sickle Cell Trait in Student Athletes

In some ways this seems like a pro-active, well-intentioned policy that could save lives. On the other hand, as discussed in the NEJM piece, the new screening policy raises a host of challenging issues:

* how will colleges inform minor players’ parents about results?
* how will the schools handle players’ privacy?…

Posted in Diagnosis, Genetics, Hematology (blood), Medical News, Under the RadarTagged , , , , , , , 2 Comments on Perspective on Screening for Sickle Cell Trait in Student Athletes

A Visit to Suffragette City

For two days I’ve been traveling on a short road-trip with my family in Upstate New York. As far as this turning to a medical lesson, all I can say is that for the first time in my life I witnessed, first-hand, the vaguely digital, elongate and eponymous geography of the fine Finger Lakes…

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Eye Care

…the office has expanded and become so systematized that when I go there I don’t feel like I’m visiting a doctor, the kind of professional who sincerely cares about my health. Instead I feel like a commodity, which I suppose I am.

Posted in health care delivery, Life as a Patient, Patient-Doctor Relationship, Physical ExaminationTagged , , , , , , , , 1 Comment on Eye Care

The Physical Exam’s Value is Not Just Emotional

But what’s also true, in a practical and bottom-line sort of way, is that a good physical exam can help doctors figure out what’s wrong with patients. If physicians were more confident – better trained, and practiced – in their capacity to make diagnoses by physical exam, we could skip the costs and toxicity of countless x-rays, CT scans and other tests.

Posted in Diagnosis, Essential Lessons, Medical Education, Patient-Doctor Relationship, Physical ExaminationTagged , , , , , 4 Comments on The Physical Exam’s Value is Not Just Emotional

Back to Basics – But Which Ones?

A front-page story on the Humanities and Medicine Program at the Mount Sinai School of Medicine, here in Manhattan, recently added to the discussion on what it takes to become a doctor in 2010. The school runs a special track for non-science majors who apply relatively early in their undergraduate years. Mount Sinai doesn’t require […]

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Suggestions to Reduce Errors in Breast Cancer Pathology

A prominent article in yesterday’s New York Times considers some troubling problems regarding inaccuracy in breast cancer diagnosis and pathology. The main point is that some women get needless, disfiguring and toxic treatments after being told they have breast cancer when, it turns out, their condition was benign. My main take is that, whenever possible, […]

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On Sergey’s Search (for a Cure for Parkinson’s Disease)

…This goes well beyond a new approach to finding a cure for Parkinson’s disease.

This story, largely based in genomics and computational advances, reflects the power of the human mind, how the gifted son of two mathematicians who fell into a particular medical situation, can use his brains, intellectual and financial resources, and creativity, to at least try to make a difference.

Posted in Empowered Patient, Future of Medicine, Genetics, Medical News, Neurology, ScienceTagged , , , , , Leave a Comment on On Sergey’s Search (for a Cure for Parkinson’s Disease)

Mind over Matter? Don’t Kid Yourself (on Stress and BC)

I learned of a new study implicating stress in reduced breast cancer survival by Twitter. A line in my feed alerted me that CNN’s health blog, “Paging Dr. Gupta,” broke embargo on the soon-to-be-published paper in the journal Clinical Cancer Research. The story – that women who undergo a stress relief program live longer after […]

Posted in Breast Cancer, cancer survival, clinical trials, Essential Lessons, Medical News, Oncology (cancer), Pseudoscience, Psychiatry, Women's HealthTagged , , , , , , , , , 3 Comments on Mind over Matter? Don’t Kid Yourself (on Stress and BC)

DNA Comes Home, or Maybe Not

Earlier this month employees at most of 7500 Walgreens pharmacies geared up to stock a new item on their shelves: a saliva sampler for personal genetic testing. On May 11, officials at Pathway Genomics, a San Diego-based biotech firm, announced they’d sell over-the-counter spit kits for around $25 through an arrangement with the retailer. A curious consumer could follow the simple package instructions and send their stuff in a plastic tube, provided in a handy box with pre-paid postage, for DNA analysis.

Posted in Diagnosis, Empowered Patient, Future of Medicine, Genetics, Medical Education, Medical News, ScienceTagged , , , , , , , 2 Comments on DNA Comes Home, or Maybe Not
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